{"id":437402,"date":"2023-02-20T11:20:40","date_gmt":"2023-02-20T10:20:40","guid":{"rendered":"https:\/\/innovationorigins.com\/?post_type=selected&amp;p=437402"},"modified":"2023-02-20T11:20:40","modified_gmt":"2023-02-20T10:20:40","slug":"technology-to-assemble-matter-in-3d","status":"publish","type":"selected","link":"https:\/\/ioplus.nl\/archive\/en\/selected\/technology-to-assemble-matter-in-3d\/","title":{"rendered":"Creating 3D objects using sound"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Scientists from the Max Planck Institute for Medical Research and the Heidelberg University have created a new technology to assemble matter in 3D. In a <a href=\"https:\/\/www.mpg.de\/19859671\/0209-mefo-creating-3d-objects-with-sound-153070-x\">press release<\/a>, the researchers described a concept which uses multiple acoustic holograms to generate pressure fields with which solid particles, gel beads and even biological cells can be printed. These results pave the way for novel 3D cell culture techniques with applications in biomedical engineering.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Additive manufacturing or<em>&nbsp;<\/em>3D printing enables the fabrication of complex parts from functional or biological materials. Conventional 3D printing can be a slow process, where objects are constructed one line or one layer at a time. Researchers now demonstrate how to form a 3D object from smaller building blocks in just a single step. \u201cWe were able to assemble microparticles into a three-dimensional object within a single shot using shaped ultrasound\u201d, says Kai Melde, postdoc in the group and first author of the study. \u201cThis can be very useful for bioprinting. The cells used there are particularly sensitive to the environment during the process\u201d, adds Peer Fischer, Professor at Heidelberg University.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The assembling method<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Sound waves exert forces on matter \u2013 a fact that any concert goer who experiences the pressure waves from a loudspeaker knows. Using high-frequency ultrasound, which is inaudible to the human ear, the wavelengths can be pushed below a millimeter into the microscopic realm, which the researcher uses to manipulate very small building blocks, like biological cells.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In their previous studies Peer Fischer and colleagues showed how to form ultrasound using acoustic holograms \u2013 3D-printed plates, which are useful to encode a specific sound field. Those sound fields, they demonstrated, can be of use to assemble materials into two-dimensional patterns. Based on this, the scientists devised a fabrication concept.<\/p>\n\n\n<div class=\"vlp-link-container vlp-layout-basic wp-block-visual-link-preview-link advgb-dyn-c6e982bd\"><a href=\"https:\/\/ioplus.nl\/archive\/en\/laio\/dutch-scale-up-dotx-control-solutions-pushes-the-boundaries-of-3d-printing\/\" class=\"vlp-link\" title=\"Dutch scale-up DoTX Control Solutions pushes the boundaries of 3d printing\"><\/a><div class=\"vlp-layout-zone-side\"><div class=\"vlp-block-2 vlp-link-image\"><\/div><\/div><div class=\"vlp-layout-zone-main\"><div class=\"vlp-block-0 vlp-link-title\">Dutch scale-up DoTX Control Solutions pushes the boundaries of 3d printing<\/div><div class=\"vlp-block-1 vlp-link-summary\">DoTX Control Solutions&#8217;\u00a05-Axis slicer software for multi-axis printers is pushing the boundaries of what 3D printing can do.\u00a0<\/div><\/div><\/div>\n\n\n<h2 class=\"wp-block-heading\">Acoustic field catches particles<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">With their new study the team was able to take their concept a step further. They capture particles and cells freely floating in water and assemble them into three-dimensional shapes. On top of that, the new method&nbsp; works with various materials, including glass or hydrogel beads and biological cells. First author Kai Melde says that \u201cthe crucial idea was to use multiple acoustic holograms together and form a combined field that can catch the particles\u201d. Heiner Kremer, who wrote the algorithm to optimize the hologram fields, adds: \u201cThe digitization of an entire 3D object into ultrasound hologram fields is computationally very demanding and required us to come up with a new computation routine\u201d.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The scientists believe that their technology is a promising platform for the formation of cell cultures and tissues in 3D. The advantage of ultrasound is that it is gentle for using biological cells and it can travel deep into tissue. This way ultrasound can remotely manipulate and push cells without harm.<\/p>\n","protected":false},"author":2583,"featured_media":493064,"template":"views\/single-selected.blade.php","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":""},"categories":[8553,76370],"tags":[129617,7738,5464,126012,67224,42478,829],"location":[24456],"internal_archives":[],"class_list":["post-437402","selected","type-selected","status-publish","has-post-thumbnail","hentry","category-digital","category-science","tag-3d-objects","tag-3d-printing-en","tag-3d-printen-nl","tag-heidelberg-university","tag-medische-technologie-2","tag-sound","tag-technology","location-germany"],"blocksy_meta":[],"acf":[],"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2023\/01\/Schermafbeelding-2023-01-17-om-12.49.13.png","coauthors":[],"author_meta":{"author_link":"https:\/\/ioplus.nl\/archive\/author\/francesco-morelli\/","display_name":"Francesco Morelli"},"relative_dates":{"created":"Posted 3 years ago","modified":"Updated 3 years ago"},"absolute_dates":{"created":"Posted on February 20, 2023","modified":"Updated on February 20, 2023"},"absolute_dates_time":{"created":"Posted on February 20, 2023 11:20 am","modified":"Updated on February 20, 2023 11:20 am"},"featured_img_caption":"","tax_additional":{"category":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/digital\/\" class=\"advgb-post-tax-term\">Digital<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/science\/\" class=\"advgb-post-tax-term\">Science<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Digital<\/span>","<span class=\"advgb-post-tax-term\">Science<\/span>"],"slug":"category","name":"Categories"},"post_tag":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/3d-objects\/\" class=\"advgb-post-tax-term\">3D objects<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/3d-printing-en\/\" class=\"advgb-post-tax-term\">3D printing<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/3d-printen-nl\/\" class=\"advgb-post-tax-term\">3D-printen<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/heidelberg-university\/\" class=\"advgb-post-tax-term\">Heidelberg University<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/medische-technologie-2\/\" class=\"advgb-post-tax-term\">medische technologie<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/sound\/\" class=\"advgb-post-tax-term\">sound<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/technology\/\" class=\"advgb-post-tax-term\">technology<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">3D objects<\/span>","<span class=\"advgb-post-tax-term\">3D printing<\/span>","<span class=\"advgb-post-tax-term\">3D-printen<\/span>","<span class=\"advgb-post-tax-term\">Heidelberg University<\/span>","<span class=\"advgb-post-tax-term\">medische technologie<\/span>","<span 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