{"id":416484,"date":"2022-10-28T12:41:23","date_gmt":"2022-10-28T10:41:23","guid":{"rendered":"https:\/\/innovationorigins.com\/?post_type=selected&p=416484"},"modified":"2022-10-28T12:41:23","modified_gmt":"2022-10-28T10:41:23","slug":"researchers-found-a-way-to-fight-tumors-with-magnetic-bacteria","status":"publish","type":"selected","link":"https:\/\/ioplus.nl\/archive\/en\/selected\/researchers-found-a-way-to-fight-tumors-with-magnetic-bacteria\/","title":{"rendered":"Researchers found a way to fight tumors with magnetic bacteria"},"content":{"rendered":"\n
Why we write about this topic:<\/summary>

Cancer is the second biggest cause of death around the world. Luckily, there is extensive research being done about the disease, slowly changing the way we approach and treat various types of tumors. This discovery is a great example of that. That’s why Innovation Origins selected this article. <\/p><\/div><\/details>\n\n\n\n

Researchers at ETH Zurich use magnetic bacteria to fight cancerous tumours. They have now found a way for these microorganisms to effectively cross blood vessel walls and subsequently colonise a tumor, writes the university in a press release<\/a>. <\/p>\n\n\n\n

Scientists around the world are researching how anti-cancer drugs can most efficiently reach the tumours they target. One possibility is to use modified bacteria as \u201cferries\u201d to carry the drugs through the bloodstream to the tumours. Researchers at ETH Zurich have now succeeded in controlling certain bacteria so that they can effectively cross the blood vessel wall and infiltrate tumour tissue.<\/p>\n\n\n

<\/a>
<\/div><\/div>
Cancer treatment of the future will outsmart tumors – Innovation Origins<\/div>
Dutch university medical centers are delving into molecular diagnostics and targeted treaments to deter early-onset cancer.<\/div><\/div><\/div>\n\n\n

Bacterial cancer therapy<\/h2>\n\n\n\n

In cell cultures and mice, Simone Sch\u00fcrle and her team have now shown that a rotating magnetic field applied to the tumor improves the bacteria\u2019s ability to cross the vascular wall near the cancerous growth. With the help of experiments and computer simulations, the ETH Zurich researchers were able to show that propelling the bacteria using a rotating magnetic field is effective for three reasons. <\/p>\n\n\n\n

First, propulsion via a rotating magnetic field is ten times more powerful than propulsion via a static magnetic field. The latter merely sets the direction and the bacteria have to move under their power. The second and most critical reason is that bacteria driven by the rotating magnetic field are constantly in motion, traveling along the vascular wall. This makes them more likely to encounter the gaps that briefly open between vessel wall cells compared to other propulsion types, in which the bacteria\u2019s motion is less explorative. And third, unlike other methods, the bacteria do not need to be tracked via imaging. Once the magnetic field is positioned over the tumor, it does not need to be readjusted.<\/p>\n\n\n\n

“We make use of the bacteria\u2019s natural and autonomous locomotion as well,” Sch\u00fcrle explains. “Once the bacteria have passed through the blood vessel wall and are in the tumor, they can independently migrate deep into its interior.” For this reason, the scientists use propulsion via the external magnetic field for just one hour \u2013 long enough for the bacteria to efficiently pass through the vascular wall and reach the tumor.<\/p>\n\n\n

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<\/div><\/div>
\u2018Cancer isn\u2019t a lifestyle disease\u2019 – Innovation Origins<\/div>
Will there be killer cells to fight cancer and a vaccine against leukemia? Gerard Bos and his team are working hard to make that happen!<\/div><\/div><\/div>\n\n\n

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