{"id":380746,"date":"2022-06-15T13:30:00","date_gmt":"2022-06-15T11:30:00","guid":{"rendered":"https:\/\/innovationorigins.com\/?post_type=selected&p=380746"},"modified":"2022-06-15T13:30:00","modified_gmt":"2022-06-15T11:30:00","slug":"new-material-for-precision-medicine-and-green-hydrogen","status":"publish","type":"selected","link":"https:\/\/ioplus.nl\/archive\/en\/selected\/new-material-for-precision-medicine-and-green-hydrogen\/","title":{"rendered":"New material for precision medicine and green hydrogen"},"content":{"rendered":"\n

The SupraBioNano Lab (SBNLab)<\/a>at the Politecnico di Milano\u2019s Department of Chemistry, Materials and Chemical Engineering “Giulio Natta\u201d, in partnership with the University of Bologna and the Aalto University of Helsinki (Finland) has, for the first time, synthesised a superfluorinated gold nanocluster, made up of a core of only 25 gold atoms, to which 18 branch-structured fluorinated molecules are linked. The project was recently published in the prestigious Nature Communications<\/em><\/a> magazine, writes the Politecnico in a press release<\/a>.<\/p>\n\n\n\n

The metal clusters are an innovative class of very complex nanomaterial, characterised by ultra-small dimensions (<2nm) and peculiar chemical-physical properties such as luminescence and catalytic activity, which encourage its application in various scientific fields of high importance in relation to modern global challenges. These include precision medicine, in which metal nanoclusters are used as innovative probes for diagnostic and therapeutic applications, and the energy transition, where they are applied as efficient catalysers for the production of green hydrogen.<\/p>\n\n\n\n

High-purity samples <\/h3>\n\n\n\n

The crystallisation of metal nanoclusters offers the possibility of obtaining high-purity samples, allowing their fine atomic structure to be determined; however, at present this remains a very difficult process to control. The methodologies developed in this study promoted the crystallisation of nanoclusters, allowing their atomic structure to be determined by means of x-ray diffraction at the Sincrotrone Elettra in Trieste. The end result is the structural description of the most complex fluorinated nano-object ever reported.<\/p>\n\n\n\n

\u201cThanks to the presence of a completely fluorinated shell, containing almost 500 fluorine atoms, the gold nanocluster is stabilised by the numerous interactions between the fluorine atoms of the binder, encouraging crystallisation\u201d, states professor Giancarlo Terraneo.<\/p>\n\n\n

<\/a>
<\/div><\/div>
Tailor-made medicine: a solution for anyone who is not a six-foot-tall man<\/div>
Medicines roll off the production line in their millions – usually in two or three standard dosages. <\/div><\/div><\/div>\n\n\n

Further research <\/h3>\n\n\n\n

\u201cIt will soon be possible to study the structure of these advanced nanomaterials at the Politecnico di Milano, where \u2013 thanks also to the grant from the Region of Lombardy \u2013 Next-GAME (Next-Generation Advanced Materials), a laboratory dedicated to the use of state-of-the-art x-ray instruments to characterise crystals, nanoparticles and colloids, is being established\u201d, concludes professor Pierangelo Metrangolo, on behalf of Next-GAME.<\/p>\n\n\n\n

The interactions between the fluorine atoms both within the nanocluster and between the nanoclusters were rationalised using quantum chemistry techniques at the University of Bologna\u2019s \u201cG. Ciamician\u201d Chemistry Department by Dr Angela Acocella and professor Francesco Zerbetto.<\/p>\n\n\n\n

Professor Valentina Dichiarante, professor Francesca Baldelli Bombelli, Dr Claudia Pigliacelli and professor Giulio Cerullo, from the Politecnico di Milano\u2019s Physics Department, also contributed to the study, looking at the nanocluster\u2019s optical characteristics and demonstrating the fluorinated binders\u2019 impact on the gold core\u2019s optical activity.<\/p>\n","protected":false},"author":2084,"featured_media":512801,"template":"","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":""},"categories":[42],"tags":[57008,86037,60390,127960],"location":[47626],"internal_archives":[],"class_list":["post-380746","selected","type-selected","status-publish","has-post-thumbnail","hentry","category-sustainability-nl","tag-aalto-university","tag-nanomaterial","tag-politecnico-of-milan","tag-university-of-bologna-2","location-italy"],"blocksy_meta":[],"acf":[],"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2022\/04\/LD4mztQY-8kpHwZ0I-Debrauwer.jpg","coauthors":[],"author_meta":{"author_link":"https:\/\/ioplus.nl\/archive\/author\/mauro-mereu\/","display_name":"Mauro Mereu"},"relative_dates":{"created":"Posted 4 years ago","modified":"Updated 4 years ago"},"absolute_dates":{"created":"Posted on June 15, 2022","modified":"Updated on June 15, 2022"},"absolute_dates_time":{"created":"Posted on June 15, 2022 1:30 pm","modified":"Updated on June 15, 2022 1:30 pm"},"featured_img_caption":"","tax_additional":{"category":{"linked":["Sustainability<\/a>"],"unlinked":["Sustainability<\/span>"],"slug":"category","name":"Categories"},"post_tag":{"linked":["Aalto University<\/a>","nanomaterial<\/a>","Politecnico of Milan<\/a>","University of Bologna<\/a>"],"unlinked":["Aalto University<\/span>","nanomaterial<\/span>","Politecnico of Milan<\/span>","University of Bologna<\/span>"],"slug":"post_tag","name":"Tags"},"language":{"linked":["EN<\/a>"],"unlinked":["EN<\/span>"],"slug":"language","name":"Tags"},"post_translations":{"linked":[],"unlinked":[],"slug":"post_translations","name":""},"location":{"linked":["Italy<\/a>"],"unlinked":["Italy<\/span>"],"slug":"location","name":"Locations"},"internal_archives":{"linked":[],"unlinked":[],"slug":"internal_archives","name":"Internal Archives"}},"series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected\/380746","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/selected"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/2084"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/512801"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=380746"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=380746"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=380746"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=380746"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=380746"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}