The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data<\/p>\n\n\n\n
A large group of international experts within the\u00a0Global Alliance for Genomics and Health (GA4GH), including users at\u00a0EMBL\u2019s European Bioinformatics Institute (EMBL-EBI)\u00a0and the\u00a0Broad Institute of MIT and Harvard, have developed the Data Use Ontology (DUO) standard. DUO annotations allow terms and definitions in data consent forms and data sharing policies to be standardised and machine readable. This helps in streamlining consent to use controlled-access biomedical datasets, writes the European Molecular Biology Laboratory in a press release<\/a>.<\/p>\n\n\n\n Human biomedical datasets often contain sensitive information about individuals. Consequently, the owner of the data must take great care when these data are being made available for secondary use by other researchers. Access and sharing of such data need to comply with legal, ethical, and informed consent rules and regulations. Navigating this complex landscape can slow research down as researchers require permission to access sensitive datasets.\u00a0<\/p>\n\n\n\n Using the Data Use Ontology (DUO) standard will streamline these processes by supporting a data authorisation and access framework for granting researchers permission to reuse biomedical datasets based on their credentials and research purposes. As described in a\u00a0recent publication\u00a0in a\u00a0special issue of\u00a0Cell Genomics<\/em>, DUO, together with the\u00a0GA4GH Passport standard, accelerates responsible sharing of biomedical datasets worldwide.<\/p>\n\n\n\n To retrieve and reuse biomedical datasets, researchers must submit a data access request to Data Access Committees. This can be a long process as a typical workflow involves manual review of applications against the data use letter that specifies how the dataset can be used, to determine whether access should be granted.<\/p>\n\n\n\n \u201cResearch consent forms often do not provide clear information about biomedical dataset sharing. Not having a standard way of representing data use conditions can really slow research down when trying to re-use those datasets,\u201d said\u00a0Melanie Courtot, Metadata Standards Coordinator at EMBL-EBI\u00a0and co-lead of the DUO development team. \u201cUsing the GA4GH DUO standard is a first step to help researchers around the globe access the biomedical data they need quickly and easily.\u201d<\/p>\n\n\n\n \u201cI\u2019m incredibly thankful to the many contributors to DUO,\u201d added Melanie. \u201cThis was a huge collaborative effort that received input from many international experts and users.\u201d<\/p>\n\n\n\n DUO is a machine-readable standard vocabulary of data use terms, aiming at describing data use conditions and automating the matching of specific datasets against the data access requests. Pairing DUO with the\u00a0GA4GH Passport\u00a0further automates this step by providing a researcher\u2019s authentication and authorisation levels.<\/p>\n\n\n\n \u201cOver 200,000 datasets worldwide have already been annotated with DUO terms and it has been successfully implemented in various institutions such as the Broad Institute and the Wellcome Sanger Institute,\u201d said\u00a0Tommi Nyr\u00f6nen, Head of Node at ELIXIR Finland, and co-lead of the GA4GH Data Use and Researcher Identities Work Stream that developed the DUO. \u201cThere\u2019s still more to be done; we want to include different data types and the\u00a0Resource Entitlement Management System\u00a0tool we are developing and deploying with EGA will leverage both DUO and Passport implementation.\u201dMoving away from manual workflows<\/h3>\n\n\n\n
A machine-readable vocabulary<\/h3>\n\n\n\n
Also interesting: <\/strong><\/em>Big data joins the fight against cancer<\/a><\/p>\n","protected":false},"author":2084,"featured_media":317677,"template":"","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":""},"categories":[34665],"tags":[125591,8192,31469,28722,54111],"location":[24456],"internal_archives":[],"class_list":["post-317674","selected","type-selected","status-publish","has-post-thumbnail","hentry","category-health","tag-biomedical-data","tag-data-en","tag-embl","tag-healthcare-en","tag-mit-en","location-germany"],"blocksy_meta":[],"acf":[],"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2022\/04\/yuf4RcCr-data-use-ontology-1000x600-FINAL-1.jpg","coauthors":[],"author_meta":{"author_link":"https:\/\/ioplus.nl\/archive\/author\/mauro-mereu\/","display_name":"Mauro Mereu"},"relative_dates":{"created":"Posted 4 years ago","modified":"Updated 4 years ago"},"absolute_dates":{"created":"Posted on November 11, 2021","modified":"Updated on November 11, 2021"},"absolute_dates_time":{"created":"Posted on November 11, 2021 10:40 am","modified":"Updated on November 11, 2021 10:40 am"},"featured_img_caption":"\u00a9 Karen Arnott\/EMBL","tax_additional":{"category":{"linked":["Health<\/a>"],"unlinked":["Health<\/span>"],"slug":"category","name":"Categories"},"post_tag":{"linked":["biomedical data<\/a>","data<\/a>","EMBL<\/a>","healthcare<\/a>","MIT<\/a>"],"unlinked":["biomedical data<\/span>","data<\/span>","EMBL<\/span>","healthcare<\/span>","MIT<\/span>"],"slug":"post_tag","name":"Tags"},"language":{"linked":["EN<\/a>"],"unlinked":["EN<\/span>"],"slug":"language","name":"Tags"},"post_translations":{"linked":[],"unlinked":[],"slug":"post_translations","name":""},"location":{"linked":["Germany<\/a>"],"unlinked":["Germany<\/span>"],"slug":"location","name":"Locations"},"internal_archives":{"linked":[],"unlinked":[],"slug":"internal_archives","name":"Internal Archives"}},"series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected\/317674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/selected"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/2084"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/317677"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=317674"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=317674"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=317674"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=317674"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=317674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}