{"id":316668,"date":"2021-11-06T10:00:00","date_gmt":"2021-11-06T09:00:00","guid":{"rendered":"https:\/\/innovationorigins.com\/?post_type=selected&amp;p=316668"},"modified":"2021-11-06T10:00:00","modified_gmt":"2021-11-06T09:00:00","slug":"studying-chemical-mixtures-harmful-effects","status":"publish","type":"selected","link":"https:\/\/ioplus.nl\/archive\/en\/selected\/studying-chemical-mixtures-harmful-effects\/","title":{"rendered":"Studying chemical mixtures\u2019 harmful effects"},"content":{"rendered":"\n<p>EU project will generate knowledge to help pinpoint substances in chemical mixtures that are harmful to human health\u2014without animal testing.<\/p>\n\n\n\n<p>People are exposed to countless natural and synthetic chemicals through food, consumer products and the environment. Traditionally, risk assessments of these chemicals are carried out one substance at a time, writes the Technical University of Denmark in a <a href=\"https:\/\/www.dtu.dk\/english\/news\/Nyhed?id=%7B69205168-1E99-493B-BA5A-6B402BDC0D53%7D\">press release<\/a>.<\/p>\n\n\n\n<p>However, research has shown that to protect people against the harmful effects of these chemicals, it is not sufficient to assess the risk posed by the chemicals one by one. In combination, chemicals with the same harmful effect can cause harm\u2014even at doses that are harmless on their own.<\/p>\n\n\n\n<p>In the new EU project PANORAMIX, researchers from 11 European universities and organizations aim to generate knowledge and develop methods that will make it possible to identify \u2019real life\u2019 chemical mixtures and assess how harmful they are to human health. The PANORAMIX project has a focus on the harmful effects of chemicals on children and the researchers will not use animal experiments.<\/p>\n\n\n\n<p>The <a href=\"https:\/\/www.food.dtu.dk\/english\">National Food Institute<\/a>, <a href=\"https:\/\/www.dtu.dk\/english\">Technical University of Denmark<\/a>, is project coordinator.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Data from Danish children play an important role<\/h3>\n\n\n\n<p>The researchers will study complex chemical extracts from food, water and umbilical cord blood that are relevant matrices for human exposure to chemicals. They will then determine which of the chemicals are responsible for harmful effects on health.<\/p>\n\n\n\n<p>The researchers will compare this information with data from the Odense Child Cohort where biological material from 2,552 children has been collected during their first 18 years of life to provide an insight into factors that affect brain development and fertility later in life. Making this connection will reveal potential long-term health effects induced by chronic exposure to chemicals.<\/p>\n\n\n\n<p>This work will enable the researchers to pinpoint and quantify the chemicals in \u2019real life\u2019 chemical mixtures, which are most likely associated with specific human health effects. The knowledge generated can be used to propose safety levels or thresholds that can guide regulators when shaping safety policies relating to chemicals.<\/p>\n\n\n\n<p><strong><em>Also interesting: <\/em><\/strong><a href=\"https:\/\/innovationorigins.com\/en\/the-chemical-quest-for-tasty-food\/\">The chemical quest for delicious food<\/a><\/p>\n","protected":false},"author":2084,"featured_media":316672,"template":"","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":""},"categories":[34665],"tags":[49004,57971,11629],"location":[56342],"internal_archives":[],"class_list":["post-316668","selected","type-selected","status-publish","has-post-thumbnail","hentry","category-health","tag-chemicals","tag-danish-technical-university","tag-food-en","location-denmark"],"blocksy_meta":[],"acf":[],"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2022\/04\/YsefOw9k-salad-g3000291db_1920-1.jpg","coauthors":[],"author_meta":{"author_link":"https:\/\/ioplus.nl\/archive\/author\/mauro-mereu\/","display_name":"Mauro Mereu"},"relative_dates":{"created":"Posted 4 years ago","modified":"Updated 4 years ago"},"absolute_dates":{"created":"Posted on November 6, 2021","modified":"Updated on November 6, 2021"},"absolute_dates_time":{"created":"Posted on November 6, 2021 10:00 am","modified":"Updated on November 6, 2021 10:00 am"},"featured_img_caption":"\u00a9 Pixabay","tax_additional":{"category":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Health<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Health<\/span>"],"slug":"category","name":"Categories"},"post_tag":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/chemicals\/\" class=\"advgb-post-tax-term\">chemicals<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/danish-technical-university\/\" class=\"advgb-post-tax-term\">Danish Technical University<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/tag\/food-en\/\" class=\"advgb-post-tax-term\">Food<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">chemicals<\/span>","<span class=\"advgb-post-tax-term\">Danish Technical University<\/span>","<span class=\"advgb-post-tax-term\">Food<\/span>"],"slug":"post_tag","name":"Tags"},"language":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/\" class=\"advgb-post-tax-term\">EN<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">EN<\/span>"],"slug":"language","name":"Tags"},"post_translations":{"linked":[],"unlinked":[],"slug":"post_translations","name":""},"location":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/location\/denmark\/\" class=\"advgb-post-tax-term\">Denmark<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Denmark<\/span>"],"slug":"location","name":"Locations"},"internal_archives":{"linked":[],"unlinked":[],"slug":"internal_archives","name":"Internal Archives"}},"series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected\/316668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/selected"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/selected"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/2084"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/316672"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=316668"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=316668"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=316668"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=316668"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=316668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}