{"id":487158,"date":"2024-09-15T10:00:00","date_gmt":"2024-09-15T08:00:00","guid":{"rendered":"https:\/\/innovationorigins.com\/?p=487158"},"modified":"2024-09-15T10:00:00","modified_gmt":"2024-09-15T08:00:00","slug":"for-robin-a-brothers-efforts-to-revolutionize-mental-healthcare","status":"publish","type":"post","link":"https:\/\/ioplus.nl\/archive\/en\/for-robin-a-brothers-efforts-to-revolutionize-mental-healthcare\/","title":{"rendered":"For Robin: A brother\u2019s efforts to revolutionize mental healthcare"},"content":{"rendered":"\n

This story was written and originally published<\/a> by the TU\/e. <\/em><\/p>\n\n\n\n

The family of EngD researcher Sander van den Borne know all too well about how a mental disorder can affect a family member. Sander\u2019s sister Robin was diagnosed at an early age and lost her battle with mental disorders at just 19 years old. Motivated by his sister\u2019s story, Van den Borne has developed a technological solution to help doctors and institutes alike to monitor patients taking serious medication for mental disorders.<\/p>\n\n\n\n

When Sander van den Borne talks about his sister Robin, all sorts of childhood memories come flooding back. \u201cWhen we were younger, we used to get up to all sorts of trouble at home,\u201d says Sander van den Borne about his childhood with his sister Robin with a smile. \u201cWe had lots of fun doing it too.\u201d<\/p>\n\n\n\n

Van den Borne is an EngD researcher at TU\/e and clinical informatician in training at Mental Healthcare Eindhoven (Geestelijke Gezondheidszorg Eindhoven (GGzE)). His EngD program is known as Clinical Informatics (CI).<\/p>\n\n\n\n

In June 2024, Van den Borne took part in TU\/e\u2019s science pitching competition Talking Science where he shared an inspiring three-minute pitch about his EngD work. He finished in a well-deserved second in the competition with a pitch based around the life of his adopted sister Robin.<\/p>\n\n\n\n

Robin\u2019s life<\/strong><\/h2>\n\n\n\n
\"\"
Sander van den Borne presenting his pitch. Photo: Bart van Overbeeke<\/figcaption><\/figure>\n\n\n\n

\u201cAt an early age, Robin was diagnosed as being bipolar and she had other mental disorders too. To manage these disorders, she needed to take medication, but as she got older, she refused to take the medication on several occasions,\u201d says Van den Borne.<\/p>\n\n\n\n

It was in the late 1990s that Robin was first diagnosed when she lived with Sander and the rest of the family in the small village of Hooge Mierde in North Brabant.<\/p>\n\n\n\n

\u201cThat was at a time in the Netherlands when it was a taboo to speak openly about such issues,\u201d says Van den Borne. \u201cAnd in particular, in a small village with a population of about 1,200, this wasn\u2019t something people spoke about.\u201d<\/p>\n\n\n\n

The medications that Robin took required constant patient monitoring by the healthcare system. In addition, Robin switched health care providers several times, which led to even more prescriptions too.<\/p>\n\n\n\n

\u201cRobin was around 10 or 11 years old when her issues with mental disorders started. Over the years, she took lots of medication and we do know that she often didn\u2019t take them according to the prescription as she got older. Added to this, Robin suffered because the healthcare system at the time didn\u2019t know how to properly treat her disorders.\u201d<\/p>\n\n\n\n

Solving a serious issue<\/strong><\/h2>\n\n\n\n

Unfortunately for Sander and his family, Robin passed away in 2009 at the age of just 19 years old. \u201cShe moved from one healthcare organization to another, and in the end, no one was really able to help her.\u201d<\/p>\n\n\n\n

Motivated by what happened to his sister and her illness, as part of his EngD research, Van den Borne set out to assess and solve a serious issue in relation to medications prescribed to patients \u2013 patient monitoring.<\/p>\n\n\n\n

Need for constant monitoring<\/strong><\/h2>\n\n\n\n

\u201cWhen you look at the medication process now, it could be improved in many ways. For an organization like Mental Healthcare Eindhoven (Geestelijke Gezondheidszorg Eindhoven (GGzE)), the process of monitoring patients is quite difficult, and the organization is looking for new ways to improve this process,\u201d says Van den Borne.<\/p>\n\n\n\n

In the case of medications for mental health disorders, monitoring is critical.<\/p>\n\n\n\n

Dosing medications<\/strong><\/h2>\n\n\n\n

\u201cThese medications can be extremely harmful to the body. If a dose is too high, it can lead to death. On the other hand, if the dose is too low it may not treat the disorder, but it can still damage the body. Thus, it\u2019s imperative that the dose is exactly right so that the patient gets the benefit from taking the medication. Nevertheless, certain medications can shorten the lifespan of people by up to 15 years.\u201d<\/p>\n\n\n\n

So, when a patient is taking specialized medication, careful monitoring is always needed, but that\u2019s not happening as much as it should.<\/p>\n\n\n\n

\u201cMy two-year study in the Netherlands confirms results from longer studies in Denmark and Australia \u2013 there are many problems with the monitoring process which leads to so-called avoidable incidents or problems. These are problems that could be circumvented with proper and dedicated patient monitoring.\u201d<\/p>\n\n\n\n

\"\"
(Photo: Bart van Overbeeke)<\/em><\/figcaption><\/figure>\n\n\n\n

The \u2018Robin system\u2019<\/h2>\n\n\n\n

Over the course of his two-year EngD research, Van den Borne set out to develop a way to improve the monitoring of patients taking certain medication.<\/p>\n\n\n\n

\u201cMedical tests need to be carried out all the time when a patient is on serious meds, such as those for mental disorders. My technological solution automates these medical tests. It\u2019s called the \u2018Robin system\u2019, named after my sister.\u201d<\/p>\n\n\n\n

Right now, when someone is prescribed medication, it\u2019s based on the primary electronic registration system of the doctor. \u201cAfter this step, the plan is for the Robin system to initiate, and it automatically orders and monitors all necessary medical tests for the patient as required by the mental health doctor and the mental healthcare standards.\u201d<\/p>\n\n\n\n

But isn\u2019t such monitoring already taking place in the healthcare system? \u201cNo, it\u2019s not, and I was very surprised to learn this at the start of the project,\u201d Van den Borne says. \u201cAnd the worrying things is that this problem isn\u2019t unique to Mental Healthcare Eindhoven.\u201d<\/p>\n\n\n\n

Manual in the head<\/strong><\/h2>\n\n\n\n

Part of the reason for the problem relates to the number of patients that an individual mental healthcare doctor must deal with.<\/p>\n\n\n\n

\u201cThey have been educated on the standards and have the \u2018manual\u2019 in their head. But doctors have more and more patients to manage. Some have doctor assistants, but this introduces another source of human error,\u201d notes Van den Borne.<\/p>\n\n\n\n

Data-driven solution<\/strong><\/h2>\n\n\n\n

As part of his research, Van den Borne devised a proof-of-concept protocol.  The aim of the protocol is to shorten the time for the ordering and assessment of medical tests for someone taking medications that can be harmful, while also making sure the right tests are ordered and results from the tests are communicated on time. If the results are not there on time, the Robin system also notifies the doctor.<\/p>\n\n\n\n

\u201cTo check on the effectiveness of a medication requires several steps. The main issue is that each of these steps represents a potential point of failure in effective monitoring. So, I sought to automate the process as much as possible using the primary patient registration system of a doctor.\u201d<\/p>\n\n\n

<\/a>
<\/div><\/div>
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Dutch universities are voicing strong concerns over proposed government budget cuts in higher education, warning of potential long-term economic and innovation damage. <\/div><\/div><\/div>\n\n\n
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Photo: Bart van Overbeeke<\/figcaption><\/figure>\n\n\n\n

Always the need for doctors<\/strong><\/h2>\n\n\n\n

According to Van den Borne, you can never optimize the doctor consultation part out of the medication process. \u201cThere will always be a doctor who prescribes medicine. But this step is executed quite well. If the doctor doesn\u2019t issue a prescription, then the patient doesn\u2019t get any medication. The \u2018Robin system\u2019 looks at what comes after and depends on lots of data.\u201d<\/p>\n\n\n\n

Van den Borne\u2019s Robin system uses data from various sources such as the doctor\u2019s registration and from the repository of ATC (Anatomical Therapeutic Code) classification for medicine.<\/p>\n\n\n\n

\u201cAn ATC classification is a unique number for the active substance within the medicine. It indicates if a patient with a given condition needs any specific monitoring and care when they are taking the medication.\u201d<\/p>\n\n\n\n

In the case of the Robin system, if a patient needs specific tests and monitoring then the system can automate the ordering of any medical tests needed by the patient.<\/p>\n\n\n\n

\u201cFor example, if a doctor prescribes clozapine (a drug used to manage schizophrenia, psychoses, movement disorders, mania, and depression, ed.), the system will instantly suggest the ordering of tests while the patient takes the medication. The doctor can approve the tests or dismiss them, but for the latter they need to provide a good reason which is noted in the system.\u201d<\/p>\n\n\n\n

\n

“The system is designed to make the doctor\u2019s job easier.”<\/p>\nSander van den Borne<\/cite><\/blockquote>\n\n\n\n

Besides having access to data on medication and the electronic patient files of the doctor, the Robin system also needs access to data from laboratory testing facilities.<\/p>\n\n\n\n

\u201cThe system is collecting data on medicines, patients, and lab tests. It\u2019s a lot of data with a lot of variables, which can pose issues for doctors. So, the system is designed to make the doctor\u2019s job easier and ensure that they don\u2019t forget any important patient tests.\u201d<\/p>\n\n\n\n

When will the system be used?<\/h2>\n\n\n\n

Van den Borne didn\u2019t get a chance to implement his proof-of-concept Robin system in institutes of hospitals over the course of his EngD research, but he has big plans for the Robin system in the future.<\/p>\n\n\n\n

\u201cI plan to implement the system in a healthcare setting from January 2025. The system will first be used by three mental healthcare nursing specialists. Then, along with my colleagues at GGzE, we\u2019ll assess if the new system has improved the medication monitoring process. If so, the system will be used by all mental healthcare specialists in Eindhoven at GGzE. My hope is that all health care institutes who prescribe medication will use Robin or a similar system to improve patient monitoring.\u201d<\/p>\n\n\n\n

Van den Borne has a central aspiration for the Robin system. \u201cI hope that we can prevent as many avoidable incidents involving medication as possible. I don\u2019t blame any doctor for what happened to my sister. Doctors must deal with so many patients and each can have intricate details about their condition. I want to inspire healthcare organizations with regards to the use of technology, and I want my system to help them as much as possible.\u201d<\/p>\n\n\n\n

\n

“I hope that we can prevent as many avoidable incidents involving medication as possible. And inspire healthcare organizations with regards to the use of technology.”<\/p>\nSander van den Borne<\/cite><\/blockquote>\n\n\n\n

And with advancements in new technologies in healthcare such as AI and digital twinning (where a virtual copy of a person\u2019s organ or entire body can be created on a computer), Van den Borne thinks his system will only improve in the future.<\/p>\n\n\n\n

\u201cAI could quickly analyze a patient’s health data and provide greater support to doctors in terms of medication monitoring. And with digital twinning one could check if a certain dose is effective or not and all without having to put the patient in danger.\u201d<\/p>\n\n\n

<\/a>
<\/div><\/div>
Decarbonizing industries is decarbonizing the heat supply<\/div>
Behind most things we use and consume daily is a specific industrial process. From making ceramic tiles to baking cookies on an industrial scale; a lot of processes need heat.<\/div><\/div><\/div>\n\n\n
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Photo: Bart van Overbeeke<\/figcaption><\/figure>\n\n\n\n

What would Robin think?<\/strong><\/h2>\n\n\n\n

Sander\u2019s research journey has been very much influenced by the life of his sister. So, what would Robin think of Sander\u2019s research?<\/p>\n\n\n\n

\u201cIt would be nice to ask her this question,\u201d says Van den Borne. \u201cBefore asking, I\u2019d tell her that I had found a solution to help ensure that she gets the right monitoring for the medication that she\u2019s taking. This minimizes the risk of accidental doses or taking the wrong medication.\u201d<\/p>\n\n\n\n

After giving his initial answer Van den Borne pauses for a moment as he realizes something important about his initial answer.<\/p>\n\n\n\n

\u201cThinking about it a bit more, I think Robin might ask \u2018Why do you need a solution when I\u2019m receiving the care that I need from a mental healthcare institute?\u2019 As a result, I\u2019d have to back-track a bit in my answer. I\u2019d explain that there are more risks in the medication process than she would assume to be from a patient point of view. I hope my explanation would clarify things for her and that she\u2019d be happy to hear that she\u2019s getting the right medication and the best monitoring possible.\u201d<\/p>\n\n\n\n

As we conclude our discussion, Van den Borne reflects on that final question in relation to Robin\u2019s opinion on his research. \u201cIt\u2019s nice to think about how I could have helped Robin. With this work though, I get the chance to help others like her who are dealing with similar problems right now. And I think Robin would think it was quite cool to have the system named after her too!\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

This story was written and originally published by the TU\/e. The family of EngD researcher Sander van den Borne know all too well about how a mental disorder can affect a family member. Sander\u2019s sister Robin was diagnosed at an early age and lost her battle with mental disorders at just 19 years old. Motivated […]<\/p>\n","protected":false},"author":2589,"featured_media":506249,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[5],"tags":[86125,86127,8952,28722,2519,132],"location":[6763],"article_type":[6758],"serie":[],"archives":[],"internal_archives":[],"reboot-archive":[82868],"class_list":["post-487158","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bio","tag-biomedical-engineering","tag-geestelijke-gezondheidszorg","tag-gezondheidszorg","tag-healthcare-en","tag-tue-en","tag-tue","location-netherlands","article_type-interview","reboot-archive-bio"],"blocksy_meta":[],"acf":{"subtitle":"Sander van den Borne defends his EngD thesis on September 20th at the school of medical physics and engineering Eindhoven, which is part of the department of Biomedical Engineering.","text_display_homepage":false},"author_meta":{"display_name":"Team IO","author_link":"https:\/\/ioplus.nl\/archive\/author\/erikdevries\/"},"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2024\/09\/csm_Sander-Banner-Image-BvOF-2024_0910_AMW_db51fa2112.jpg","coauthors":[],"tax_additional":{"categories":{"linked":["BIO+<\/a>"],"unlinked":["BIO+<\/span>"]},"tags":{"linked":["biomedical engineering<\/a>","geestelijke gezondheidszorg<\/a>","gezondheidszorg<\/a>","healthcare<\/a>","TU\/e<\/a>","TU\/e<\/a>"],"unlinked":["biomedical engineering<\/span>","geestelijke gezondheidszorg<\/span>","gezondheidszorg<\/span>","healthcare<\/span>","TU\/e<\/span>","TU\/e<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 2 years ago","modified":"Updated 2 years ago"},"absolute_dates":{"created":"Posted on September 15, 2024","modified":"Updated on September 15, 2024"},"absolute_dates_time":{"created":"Posted on September 15, 2024 10:00 am","modified":"Updated on September 15, 2024 10:00 am"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/487158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/2589"}],"replies":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/comments?post=487158"}],"version-history":[{"count":0,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/487158\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/506249"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=487158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=487158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=487158"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=487158"},{"taxonomy":"article_type","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/article_type?post=487158"},{"taxonomy":"serie","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/serie?post=487158"},{"taxonomy":"archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/archives?post=487158"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=487158"},{"taxonomy":"reboot-archive","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/reboot-archive?post=487158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}