{"id":274774,"date":"2021-02-20T17:00:24","date_gmt":"2021-02-20T16:00:24","guid":{"rendered":"http:\/\/innovationorigins.com\/?p=274774"},"modified":"2021-02-20T17:00:24","modified_gmt":"2021-02-20T16:00:24","slug":"stress-meter-is-a-groundbreaking-invention","status":"publish","type":"post","link":"https:\/\/ioplus.nl\/archive\/en\/stress-meter-is-a-groundbreaking-invention\/","title":{"rendered":"Stress meter is a groundbreaking invention"},"content":{"rendered":"\n<p id=\"block-c65bc3e4-eead-4adf-873a-7fc2b308a184\">Stress is one of the biggest health risks people have to contend with. But it is not always so obvious when someone is suffering from it and what form that stress takes. Up until now, it has not been possible to measure stress levels in an objective way. Therefore, the invention of a sensor chip that can measure concentrations of the stress hormone cortisol in human sweat can justifiably be hailed as a major breakthrough.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><em>Doctors will in future be able to better understand and treat stress-related conditions, such as burnout and obesity, through near-continuous monitoring.<\/em><\/p><\/blockquote>\n\n\n\n<p id=\"block-df47c5d3-b658-4f7e-bde7-21f3c88f5b19\">The small portable sensor was developed by engineers at the <em>Nanoelectronic Devices Laboratory<\/em> (Nanolab) of the <em>\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne<\/em> (EPFL) in Switzerland. The device can be attached directly onto a patient&#8217;s skin. Doctors will in future be able to better understand and treat stress-related conditions, such as burnout and obesity, through near-continuous monitoring.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"block-cbdbebc5-a132-4bb3-9903-7fb41b7b7e8a\">Measuring cortisol<\/h3>\n\n\n\n<p>The device incorporates a transistor and an electrode made of graphene,  which offers a high range of sensitivity due to its unique properties. The graphene is functionalized by <em>aptamers<\/em>. These are short fragments of single-stranded DNA or RNA that have the ability to bind to specific compounds. The aptamer in EPFL&#8217;s device has a negative charge. When it comes into contact with cortisol, it immediately captures the hormone, causing the strands to fold on top of each other. This then moves the charge closer to the electrode surface. The device then detects the charge and can thereby measure the cortisol concentration that is present in sweat.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"block-5b0b1d39-eaee-4592-b8f6-4a14ec358dcb\">Stress meter<\/h3>\n\n\n\n<p>Cortisol is a <em>corticosteroid hormone<\/em> that is made in the<em> adrenal cortex <\/em>from cholesterol. Its secretion is regulated by the <em>adrenocorticotropic hormone<\/em> (ACTH), which is produced by the <em>adeneohypophysis<\/em>.<\/p>\n\n\n\n<p>Cortisol performs essential functions in the human body, such as regulating metabolism, blood sugar and blood pressure. It also affects the immune system and cardiovascular functions.<\/p>\n\n\n\n<p id=\"block-ed9e6ea7-95c7-4831-bf35-7dd5d8cdf867\">When a person finds themselves in a stressful situation, cortisol is the hormone that takes over. It instructs the body to send needed energy to the brain, muscles and heart. When the body makes too much or not enough cortisol, it can seriously damage an individual&#8217;s health. This in turn potentially leads to obesity, cardiovascular disease, depression or burnout.<\/p>\n\n\n\n<p id=\"block-bc62e29f-4bba-4867-95e2-e655bb6ff04b\"><strong><em>Read about another invention that measures heart rate variability <a href=\"https:\/\/innovationorigins.com\/alphabeats-partners-with-kenkou-for-stress-measurement-without-the-use-of-wearables\/\">here<\/a>.<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Stress is one of the biggest health risks people have to contend with. But it is not always so obvious when someone is suffering from it and what form that stress takes. Up until now, it has not been possible to measure stress levels in an objective way. Therefore, the invention of a sensor chip [&hellip;]<\/p>\n","protected":false},"author":1788,"featured_media":524183,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[34665],"tags":[58779,56521,58784,58786,27509,33828,58788],"location":[52892],"article_type":[],"serie":[],"archives":[],"internal_archives":[],"reboot-archive":[],"class_list":["post-274774","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-cortisol","tag-ecole-polytechnique-federale-de-lausanne","tag-hormone-levels","tag-nanoelectronic-devices-laboratory","tag-newsletter-en","tag-stress-en","tag-stress-meter","location-switzerland"],"blocksy_meta":[],"acf":{"subtitle":"This portable sensor chip - the stress meter - which can measure levels of the stress hormone cortisol present in human sweat, is a major breakthrough.","text_display_homepage":false},"author_meta":{"display_name":"Ewout Kieckens","author_link":"https:\/\/ioplus.nl\/archive\/author\/ewout-kieckens\/"},"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2021\/02\/Webp.net-resizeimage-26-300x169.jpg","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Health<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Health<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Cortisol<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">\u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">hormone levels<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Nanoelectronic Devices Laboratory<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Newsletter<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">stress<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">stress meter<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Cortisol<\/span>","<span class=\"advgb-post-tax-term\">\u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne<\/span>","<span class=\"advgb-post-tax-term\">hormone levels<\/span>","<span class=\"advgb-post-tax-term\">Nanoelectronic Devices Laboratory<\/span>","<span class=\"advgb-post-tax-term\">Newsletter<\/span>","<span class=\"advgb-post-tax-term\">stress<\/span>","<span class=\"advgb-post-tax-term\">stress meter<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 5 years ago","modified":"Updated 5 years ago"},"absolute_dates":{"created":"Posted on February 20, 2021","modified":"Updated on February 20, 2021"},"absolute_dates_time":{"created":"Posted on February 20, 2021 5:00 pm","modified":"Updated on February 20, 2021 5:00 pm"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/274774","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/1788"}],"replies":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/comments?post=274774"}],"version-history":[{"count":0,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/274774\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/524183"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=274774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=274774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=274774"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=274774"},{"taxonomy":"article_type","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/article_type?post=274774"},{"taxonomy":"serie","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/serie?post=274774"},{"taxonomy":"archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/archives?post=274774"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=274774"},{"taxonomy":"reboot-archive","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/reboot-archive?post=274774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}