{"id":219821,"date":"2020-04-23T16:15:23","date_gmt":"2020-04-23T14:15:23","guid":{"rendered":"https:\/\/innovationorigins.com\/?p=219821"},"modified":"2020-04-23T16:15:23","modified_gmt":"2020-04-23T14:15:23","slug":"anti-rheumatism-drug-that-also-works-on-covid-19","status":"publish","type":"post","link":"https:\/\/ioplus.nl\/archive\/en\/anti-rheumatism-drug-that-also-works-on-covid-19\/","title":{"rendered":"Anti-rheumatism drug that also works on COVID-19"},"content":{"rendered":"<p>The search for a vaccine against COVID-19 will take months, perhaps even years. Until that time, a drug that can combat the worst symptoms of the virus would be worth its weight in gold. The anti-malarial drug <em>Hydroxychloroquine<\/em>, pushed by Donald Trump, is unlikely to deliver that. But the German <a href=\"https:\/\/www.fau.eu\/2020\/04\/22\/news\/research\/anti-inflammatory-drugs-protect-against-covid-19\/\">Friedrich-Alexander University Erlangen-N\u00fcrnberg<\/a> (FAU) might have found something that does work.<\/p>\n<p>A research team from the FAU has demonstrated in a study that drugs that are designed to treat autoimmune diseases are capable of inhibiting COVID-19 infections even before the virus has spread into the body.<\/p>\n<figure id=\"attachment_219806\" aria-describedby=\"caption-attachment-219806\" style=\"width: 300px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-219806\" src=\"https:\/\/archive.ioplus.nl\/wp-content\/uploads\/2020\/04\/Rheuma-Uniklinikum-Erlangen.jpg\" alt=\"\" width=\"300\" height=\"200\" \/><figcaption id=\"caption-attachment-219806\" class=\"wp-caption-text\">The FAU is an authority when it comes to the treatment of autoimmune diseases such as rheumatism.<\/figcaption><\/figure>\n<p>The study, published in the scientific journal <a href=\"https:\/\/www.nature.com\/articles\/s41577-020-0312-7\"> Nature Reviews Immunology<\/a>, uses what are known as <em>cytokine blockers<\/em> or <em>cytokine inhibitors<\/em>. These are normally used for the treatment of patients with autoimmune diseases such as rheumatism, gastrointestinal inflammation, and psoriasis.<\/p>\n<h3>Autoimmune diseases<\/h3>\n<p>A study of 1000 test subjects revealed that those test subjects who had taken the cytokine blockers because of their autoimmune conditions were better protected against COVID-19. More so than the other test subjects who were part of a group of volunteer nurses and doctors who hadn&#8217;t taken that medicine.<\/p>\n<blockquote><p>&#8220;It seems that the cytokine inhibitors limit the infection with SARS-COV-2 viruses from the outset. This prevents the production of any antibodies,&#8221; says Professor Georg Schett from the FAU.<\/p><\/blockquote>\n<p>COVID-19 is known to trigger a strong immune response that leads to inflammation of the <em>alveoli<\/em> (air sacs) in the lungs. This, in turn, disrupts the gas exchange in the lungs. This inflammatory reaction is caused by <em>cytokine<\/em>, a substance that serves as a messenger in the body. Several of these messenger substances play an important role in diseases such as rheumatism, gastrointestinal inflammation, and psoriasis and can, therefore, be counteracted with cytokine inhibitors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The search for a vaccine against COVID-19 will take months, perhaps even years. Until that time, a drug that can combat the worst symptoms of the virus would be worth its weight in gold. The anti-malarial drug Hydroxychloroquine, pushed by Donald Trump, is unlikely to deliver that. But the German Friedrich-Alexander University Erlangen-N\u00fcrnberg (FAU) might [&hellip;]<\/p>\n","protected":false},"author":1723,"featured_media":518765,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[34665],"tags":[50299,48733,48127,34157,50301,39261,48131],"location":[],"article_type":[],"serie":[],"archives":[],"internal_archives":[],"reboot-archive":[],"class_list":["post-219821","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-autoimmune-dieseases","tag-coronavirus-en","tag-covid-19","tag-immune-system","tag-lungs","tag-rheumatism","tag-sars-cov-2"],"blocksy_meta":[],"acf":{"subtitle":"","text_display_homepage":false},"author_meta":{"display_name":"Maurits Kuypers","author_link":"https:\/\/ioplus.nl\/archive\/author\/maurits-kuypers\/"},"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2020\/04\/Rheuma_Colourbox-300x200.jpg","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Health<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Health<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">autoimmune dieseases<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Coronavirus<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">COVID-19<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">immune system<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">lungs<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">Rheumatism<\/a>","<a href=\"https:\/\/ioplus.nl\/archive\/en\/category\/health\/\" class=\"advgb-post-tax-term\">SARS-CoV-2<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">autoimmune dieseases<\/span>","<span class=\"advgb-post-tax-term\">Coronavirus<\/span>","<span class=\"advgb-post-tax-term\">COVID-19<\/span>","<span class=\"advgb-post-tax-term\">immune system<\/span>","<span class=\"advgb-post-tax-term\">lungs<\/span>","<span class=\"advgb-post-tax-term\">Rheumatism<\/span>","<span class=\"advgb-post-tax-term\">SARS-CoV-2<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 6 years ago","modified":"Updated 6 years ago"},"absolute_dates":{"created":"Posted on April 23, 2020","modified":"Updated on April 23, 2020"},"absolute_dates_time":{"created":"Posted on April 23, 2020 4:15 pm","modified":"Updated on April 23, 2020 4:15 pm"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/219821","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/1723"}],"replies":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/comments?post=219821"}],"version-history":[{"count":0,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/219821\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/518765"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=219821"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=219821"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=219821"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=219821"},{"taxonomy":"article_type","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/article_type?post=219821"},{"taxonomy":"serie","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/serie?post=219821"},{"taxonomy":"archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/archives?post=219821"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=219821"},{"taxonomy":"reboot-archive","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/reboot-archive?post=219821"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}