Researchers at the TU\/e have found a cheaper way to make an expensive cancer drug. Former bachelor student Daphne van Scheppingen discovered the method in 2011, but now a collaboration has been started between researchers from TU\/e, Syncom B.V. and the Antoni van Leeuwenhoekzhuis, to produce the cancer drug Z-Endoxifen.<\/p>\n
The bachelor’s student and her project supervisor Dr Lech-Gustav Milroy discovered that an expensive purification method (HPLC) was not necessary and that Z-Endoxifen could also be purified by a much cheaper process. The Groningen company Syncom then went on to improve this production method, so that the medicine can also be made in a large quantity. Finally, researchers from the Antoni van Leeuwenhoekzhuis proved that this approach indeed yielded pure Z-endoxifen and that the alternative cleaning method is effective. The drug still costs about 75,000 euros per gram, but with the new production process, the production costs can be a thousand times lower. Medical research groups no longer have to go to expensive producers to do research into the effects of the drug; the simplified process means that they can now produce it themselves in a much cheaper way.<\/p>\n
Before the drug is available to patients, the new production method must be further scaled up to industrial production. The researchers expect that this will take about a year of research. More research is also needed into the effect of the drug, which can last between one and six years.<\/p>\n
Photo: Bart van Overbeeke<\/p>\n","protected":false},"excerpt":{"rendered":"
Researchers at the TU\/e have found a cheaper way to make an expensive cancer drug. Former bachelor student Daphne van Scheppingen discovered the method in 2011, but now a collaboration has been started between researchers from TU\/e, Syncom B.V. and the Antoni van Leeuwenhoekzhuis, to produce the cancer drug Z-Endoxifen. The bachelor’s student and her […]<\/p>\n","protected":false},"author":1632,"featured_media":503482,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[42],"tags":[7462,4261,2519,132],"location":[],"article_type":[],"serie":[],"archives":[],"internal_archives":[],"reboot-archive":[],"class_list":["post-135164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sustainability-nl","tag-cancer","tag-research","tag-tue-en","tag-tue"],"blocksy_meta":[],"acf":{"subtitle":"","text_display_homepage":false},"author_meta":{"display_name":"Frans van Beveren","author_link":"https:\/\/ioplus.nl\/archive\/author\/frans-van-beveren\/"},"featured_img":"https:\/\/ioplus.nl\/archive\/wp-content\/uploads\/2018\/04\/csm_BvOF-2018_0321_NP-Lech-Milroy-demo-filtration-for-pure-Z-endoxifen_c5f572c08f.jpg","coauthors":[],"tax_additional":{"categories":{"linked":["Sustainability<\/a>"],"unlinked":["Sustainability<\/span>"]},"tags":{"linked":["cancer<\/a>","research<\/a>","TU\/e<\/a>","TU\/e<\/a>"],"unlinked":["cancer<\/span>","research<\/span>","TU\/e<\/span>","TU\/e<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 8 years ago","modified":"Updated 8 years ago"},"absolute_dates":{"created":"Posted on April 5, 2018","modified":"Updated on April 5, 2018"},"absolute_dates_time":{"created":"Posted on April 5, 2018 3:00 pm","modified":"Updated on April 5, 2018 3:00 pm"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/135164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/users\/1632"}],"replies":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/comments?post=135164"}],"version-history":[{"count":0,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/posts\/135164\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media\/503482"}],"wp:attachment":[{"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/media?parent=135164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/categories?post=135164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/tags?post=135164"},{"taxonomy":"location","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/location?post=135164"},{"taxonomy":"article_type","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/article_type?post=135164"},{"taxonomy":"serie","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/serie?post=135164"},{"taxonomy":"archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/archives?post=135164"},{"taxonomy":"internal_archives","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/internal_archives?post=135164"},{"taxonomy":"reboot-archive","embeddable":true,"href":"https:\/\/ioplus.nl\/archive\/wp-json\/wp\/v2\/reboot-archive?post=135164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}